{"id":758,"date":"2018-09-19T12:11:43","date_gmt":"2018-09-19T12:11:43","guid":{"rendered":"https:\/\/dubaistdclinic.com\/news\/?p=758"},"modified":"2019-04-22T15:06:46","modified_gmt":"2019-04-22T15:06:46","slug":"penicillin-g-benzathine-bicillin-la-shortage","status":"publish","type":"post","link":"https:\/\/dubaistdclinic.com\/news\/?p=758","title":{"rendered":"Penicillin G benzathine (Bicillin-LA) Shortage"},"content":{"rendered":"<div class=\" module-typeE\">\n<div>\n<p>The FDA reports the benzathine pencillin G shortage was resolved as of 5\/8\/2018.<\/p>\n<\/div>\n<\/div>\n<h3>Message from CDC regarding the recent shortage of Penicillin G benzathine in the United States<\/h3>\n<p>Penicillin G benzathine is the recommended treatment for syphilis and the only recommended treatment for pregnant women infected or exposed to syphilis. Pfizer, the sole manufacturer of penicillin G benzathine (Bicillin L-A\u00ae) in the United States continues to experience a manufacturing delay of this product. CDC is working with FDA\u2019s Drug Shortage Staff and Pfizer to address this situation.<\/p>\n<p>Until normal quantities of penicillin G benzathine (Bicillin L-A\u00ae) are available, CDC suggests the following:<\/p>\n<ol>\n<li>Refrain from the use of penicillin G benzathine (Bicillin L-A\u00ae) for treatment of other infectious diseases (e.g., streptococcal pharyngitis) where other effective antimicrobials are available.<\/li>\n<li>Adhere to the recommended dosing regimen of 2.4 million units of penicillin G benzathine IM for the treatment of primary, secondary and early latent syphilis (i.e., early syphilis) as outlined in the\u00a0<a class=\"tp-link-policy\" href=\"https:\/\/www.cdc.gov\/std\/tg2015\/syphilis.htm\">2015 STD Treatment Guidelines<\/a>. Additional doses to treat early syphilis do not enhance efficacy, including in patients living with HIV infection.<\/li>\n<li>Contact your pharmacists\/distributors to procure penicillin G benzathine (Bicillin L-A\u00ae), if you do not have product readily available. \u00a0If product reaches a critical supply level of three weeks or less, contact Pfizer. The company contact information can be found on the<a class=\"tp-link-policy tp-external-link-fix\" href=\"http:\/\/www.accessdata.fda.gov\/scripts\/drugshortages\/dsp_ActiveIngredientDetails.cfm?AI=Penicillin%20G%20Benzathine%20(Bicillin%20L-A)%20Injection&amp;st=c&amp;tab=tabs-1\" target=\"_self\" rel=\"noopener noreferrer\">\u00a0FDA\u2019s Drug Shortage Website<\/a>. \u00a0Also, alert your state or local STD Prevention Program of any shortage of penicillin G benzathine (Bicillin L-A\u00ae) as they are informing CDC of any shortages.<\/li>\n<li>Direct questions about syphilis clinical management to an infectious disease specialist or the on-line National Network of STD Clinical Prevention Training Centers (NNPTC) STD Clinical Consultation Network (<a class=\"tp-link-policy tp-external-link-fix\" href=\"https:\/\/www.stdccn.org\/\" target=\"_self\" rel=\"noopener noreferrer\">https:\/\/www.stdccn.org<\/a>\u00a0).<\/li>\n<\/ol>\n<p>More information on recommended syphilis treatment and clinical management can be found in the\u00a0<a class=\"tp-link-policy\" href=\"https:\/\/www.cdc.gov\/std\/tg2015\/syphilis.htm\">2015 STD Treatment Guidelines<\/a>(<a class=\"tp-link-policy\" href=\"https:\/\/www.cdc.gov\/std\/tg2015\/syphilis.htm\">\/std\/tg2015\/syphilis.htm<\/a>). CDC is not recommending any changes to these treatment recommendations for patients with syphilis.<\/p>\n<p>Additional information on the availability of penicillin G benzathine (Bicillin L-A\u00ae) can be found at<a class=\"tp-link-policy\" href=\"https:\/\/www.cdc.gov\/std\/treatment\/drugnotices\/bicillinshortage.htm\">\u00a0\/std\/treatment\/drugnotices\/bicillinshortage.htm<\/a>\u00a0or on the\u00a0<a class=\"tp-link-policy tp-external-link-fix\" href=\"http:\/\/www.accessdata.fda.gov\/scripts\/drugshortages\/dsp_ActiveIngredientDetails.cfm?AI=Penicillin%20G%20Benzathine%20(Bicillin%20L-A)%20Injection&amp;st=c&amp;tab=tabs-1\" target=\"_self\" rel=\"noopener noreferrer\">FDA\u2019s Drug Shortage website<\/a><\/p>\n<p>If you have any questions about the penicillin G benzathine (Bicillin L-A\u00ae) shortage, please contact your state or local health department\u2019s STD Prevention Program. Please share this guidance with other healthcare providers and pharmacists.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The FDA reports the benzathine pencillin G shortage was resolved as of 5\/8\/2018. Message from CDC regarding the recent shortage of Penicillin G benzathine in the United States Penicillin G benzathine is the recommended treatment for syphilis and the only recommended treatment for pregnant women infected or exposed to syphilis. Pfizer, the sole manufacturer of [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[49,2],"tags":[],"_links":{"self":[{"href":"https:\/\/dubaistdclinic.com\/news\/index.php?rest_route=\/wp\/v2\/posts\/758"}],"collection":[{"href":"https:\/\/dubaistdclinic.com\/news\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dubaistdclinic.com\/news\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dubaistdclinic.com\/news\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dubaistdclinic.com\/news\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=758"}],"version-history":[{"count":3,"href":"https:\/\/dubaistdclinic.com\/news\/index.php?rest_route=\/wp\/v2\/posts\/758\/revisions"}],"predecessor-version":[{"id":951,"href":"https:\/\/dubaistdclinic.com\/news\/index.php?rest_route=\/wp\/v2\/posts\/758\/revisions\/951"}],"wp:attachment":[{"href":"https:\/\/dubaistdclinic.com\/news\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=758"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dubaistdclinic.com\/news\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=758"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dubaistdclinic.com\/news\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=758"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}